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Scroll down this page to see the effects of different insulin doses and regimens on the blood glucose profile of an example insulin-dependent diabetic patient.
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The first graph in the panel below shows a 24-hour blood glucose profile for a typical patient (in red). Her carbohydrate intake is shown in grams on the second graph (in green).
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The next panel below shows the patient's simulated plasma insulin level on the upper graph (in red), and her insulin regimen of Actrapid (in red) and Lente (in green) on the lower graph.
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It has taken a lot of effort to stabilise this girl's blood glucose profile. However, she still often goes 'hypo' in the middle of the day, especially between breakfast and lunch. She is on a slightly unusual regimen taking a short acting insulin preparation three times per day, with an intermediate acting preparation twice a day - at lunchtime and before bed. Can you improve her glycaemic control, and get rid of her 'hypo' at 10:00 AM? Hint: for a start try increasing the carbohydate content of her breakfast...
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Below is a data entry form showing this example patient's carbohydrate intake, insulin injection regimen, as well as other clinical variables such as weight and renal function. Try changing any of these fields to modify the regimen and click on the 'Run Simulation' button at the bottom of the page. This will result in the effects of the changes being displayed in your Web browser window.
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