Scroll down this page to see the effects of different insulin doses and regimens on the blood glucose profile of an example insulin-dependent diabetic patient.
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The first graph in the panel below shows a 24-hour blood glucose profile for a typical patient (in red). His carbohydrate intake is shown in grams on the second graph (in green).
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The next panel below shows the patient's simulated plasma insulin level on the upper graph (in red), and his insulin regimen of Humulin S insulin (in red) and intermediate-acting Humulin I insulin (in green) on the lower graph.
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This elderly man is on a twice daily regimen of short and intermediate-acting insulin preparations. Unfortunately, his eyesight is failing and although he is on the waiting list for a cataract operation, this could take some time. His wife heard about premixed (biphasic) insulin preparations and thought this might help him, saving him from having to mix the individual preparations within the syringe. Using the facilties in the main AIDA on-line simulator see if you can simulate case scenario number 0029 to provide him with such a premixed twice daily insulin regimen.
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Below is a data entry form showing this example patient's carbohydrate intake, insulin regimen, as well as other clinical variables such as weight and renal function. Try changing any of these fields to modify the regimen and click on the 'Run Simulation' button at the bottom of the page. This will result in the effects of the changes being displayed in your Web browser window.
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