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Diabetes Developments - A blog on latest developments in diabetes by David Mendosa

Comparing Insulins for Type 2s

April 5th, 2009 · 4 Comments

Some of our doctors don’t help us when they use insulin as a threat: “Unless you reduce your blood glucose, I am going to have to put you on insulin.”

So it’s no surprise that many of us who have type 2 diabetes think we have failed when our doctors prescribe it. This comes from thinking of injecting insulin as a last resort.

It isn’t. More and more of us are now starting to take insulin as soon as our doctors have diagnosed our type 2 diabetes. Probably half of the men in my diabetes support group started taking insulin as a first choice.
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Posted in: Diabetes Medication

Comparing Low-Carb and Low-Glycemic

December 28th, 2008 · 7 Comments

Nobody ever compared whether a low-carb or a low-glycemic diet works better to control our blood glucose levels. Until now.

Both diets improved A1C levels and helped participants in a 24-week study to lose weight. But the low-carb group did a lot better.

Five doctors at the Duke University Medical Center in Durham, North Carolina, just reported their results in the journal Nutrition & Metabolism. Led by Eric Westman, M.D., the study, “Effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus,” appeared on December 19.
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Posted in: Diabetes Diet

Regenerating Islet Cells

December 10th, 2008 · 2 Comments

Maybe it won’t cure diabetes. But a compound slated to begin a new Phase 2b clinical trial early next year stands a good chance of knocking diabetes back into remission.

Almost never do I write about new drugs unless they are at least in in the final stage of development, a Phase 3 trial. The odds are against them.

Of 100 drugs for which developers submit investigational new drug applications to the Food and Drug Administration for approval, about 70 will successfully complete Phase 1 trials and go on to Phase 2. About 33 of the original 100 will complete Phase 2 and go to Phase 3. And 25 to 30 of the original 100 will clear Phase 3.
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Posted in: Diabetes Medication

Statin Rage

November 12th, 2008 · 12 Comments

People seldom make me angry any more. When another driver cut me off yesterday, I didn’t even flip him the finger or honk my horn. I just figured that he was in a bigger hurry than I was.

Recently doctors have determined that when we are younger and when we are older we are happier than when we are middle-aged. That can’t be generally true, because I still remember my miserable youth.

My life instead has been one of increasing happiness. I’m much more likely to shed tears of joy, as I did on the evening of November 4, than to weep with rage.
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Posted in: Diabetes Medication

Using Expired Medicine

October 6th, 2008 · 2 Comments

When we act like responsible adults, we always look at the expiration dates on the containers of prescription medicine and over-the-counter drugs that we use. Just to give one example, I can’t count the number of times that I have tossed old aspirin tablets.

Now, it turns out, I was throwing away my money.

From now on I will be saving money after reading an article in the current issue of my favorite health newsletter, which I subscribe to the old-fashioned way, on paper. The article, “Out on a date” in the October issue of the “UC Berkeley Wellness Letter,” explains that expiration dates are guarantees that prescription and over-the-counter drugs will be both potent and safe until then. But they don’t mean that after the expiration date, they won’t be effective or safe.
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Posted in: Diabetes Medication

Living Longer with Byetta

August 11th, 2008 · 26 Comments

The diabetes drug Byetta can help us control our blood glucose and lose weight. That’s huge — and just the beginning of the story.

Full disclosure: I own 100 shares of stock in Amylin, the company that developed Byetta.

About a year ago, after the Scientific Sessions of the American Diabetes Association in Chicago, I reported here how Byetta can reduce our risk of heart attacks and strokes. These are the most common and deadly complications of diabetes.

Now a study presented at the ADA’s recent Scientific Sessions in San Francisco indicates that the reduced risk to our hearts may lead to previously unheard of benefits. Taking Byetta can lower our chance of dying compared with other diabetes drugs. The Times says that the chance of dying while taking Byetta is about 75 percent lower than on the other drugs.
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Posted in: Diabetes Developments, Diabetes Medication

Pycnogenol for Diabetes Control

June 19th, 2008 · 2 Comments

Just as I was about to stop taking Pycnogenol, along comes a high quality study that convinced me to keep on using this supplement.

I have my suspicions about all supplements and have announced them here. My most recent previous article here shows that short list of those remaining in my favor.
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Posted in: Diabetes Medication

My Supplements

June 15th, 2008 · 13 Comments

One of the questions that readers ask me the most is what supplements I take. While I respond to individual email requests answering their questions, until now I have resisted writing generally on this topic.

I do study supplements, but am no expert. Eventually, however, I’ve realized that no one is. Certainly not our doctors, most of whom don’t know or care the first thing about supplements.
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Posted in: Diabetes Medication

The Cost of Weight Loss

May 22nd, 2008 · No Comments

Don’t kid yourself. Losing weight can be an expensive proposition. I know.

It’s cost me many thousands of dollars in the two and one-half years since I started taking Byetta. And then when I started to eat low-carb last December, the costs went up.
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Posted in: Diabetes Complications, Exercise For Diabetes

Announcing Our Weight

February 17th, 2008 · No Comments

Dirk Baeuerle has a nice desk job in Alabama working for an architect. It doesn’t require much physical effort and he hadn’t been getting much exercise.

He also ate too much. When he weighted himself in January 1, 2006, he was shocked to see that the scales told him that he weighed 375 pounds. Even though he’s 6′ 1″ tall he knew this was far too much.
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Posted in: Diabetes Medication, Psychosocial

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